Clarksville is a town in Mecklenburg county in the U.S. state of Virginia, near the southern border of the commonwealth. The population was 1,139 at the 2010 census. Since the town has numerous buildings of the 18th-, 19th-, and early 20th-century architecture, the downtown area of Clarksville has been designated a Historic District on the National Register of Historic Places and Virginia's Historic Register. Clarksville claims the title of Virginia's only Lakeside town. Nearby the town of Clarksville is Occoneechee State Park.The town is located on Kerr Lake, which is also known as Buggs Island Lake. The 50,000-acre lake is popular for boating and fishing; especially for catfish and many varieties of freshwater bass including largemouth bass, striped bass and crappie.The Virginia Lake Festival is held annually at Clarksville during the third weekend of July.